I just finished a video conference with the Computer-Assisted Language Learning conference for Latin America. They were in Durango, Mexico; I was sitting in my living room in Puyallup, Washington. While video conferencing is not new, this is my first time using Skype for this type of video conferencing. What was unique for me was that this was a cross-platform video conference: I was using a Macintosh and they were using a Windows computer. I was able to see the audience and the screen while I was presenting (to make sure that we were on the same slide). Other than it being early in the morning for me, and my voice had not warmed up, I was fairly pleased with the results. I think they were pleased also.
At MacWorld, I also saw a demonstration of the new iChat in the next version of OS X, which would allow screen sharing with another Macintosh on the Internet. That looks like a great way to conduct these types of video presentations. However, until the rest of the world wakes up to the superiority of the Macintosh, there will be few opportunities to use this tool (can you tell that I am an Apple Distinguished Educator?). For now, I will use Skype and may try doing SkypeCasting.